MTB Drug-resistance REAL-TIME PCR Genotyping Kit (48 tests)

Kits are manufactured by ‘whole cycle production’ principle under stringent conditions, meeting requirements of GMP standard.

Kits are based on real-time polymerase chain reaction (PCR) technology allowing fast and highly sensitive detection of pathogen with minimum risk of contamination

The suggested approach is more flexible  in terms of experiment setup and hence is more rational and cost-effective compared to ‘closed’ solutions

Kits are designed in collaboration with state medicine authorities of a highest expert level

The genotyping kit includes mutations accounting for 90% of isoniazid and rifampicin resistance cases

The original genotyping approach is based on melting curve analysis, which is characterized by high specificity, reproducibility and resistance to unaccounted adjacent sequence variations 

The original software allows automated interpretation of results and genotype calling

The genotyping kit is intended for detection and allelic discrimination of the genetic polymorphisms of Mycobacteria associated with Rifampicin-resistance and Isoniazid-resistance. The following mutations can be detected: katG:315AGC>ACC, inhA:15C>T, (for Isoniazid-resistance) and rpoB:516GAC>GTC, rpoB:526CAC>GAC, rpoB:526CAC>TAC, rpoB:531TCG>TTG (for Rifampicin-resistance).